Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,6,6-trimethyl-4-(2,4,6-trimethyl-phenyl)-[1,2]oxazinane-3,5-dione | IC50 is 0.076 mM for the herbicide-sensitive biotype and 0.227 mM for the herbicide-resistant biotype | Eleusine indica | |
2,6,6-trimethyl-4-(2,4,6-trimethyl-phenyl)-[1,2]oxazinane-3,5-dione | IC50 is 0.051 mM for the herbicide-sensitive biotype and 0.067 mM for the herbicide-resistant biotype | Setaria viridis | |
2-[1-[(E)-allyloxyimino]-propyl]-5-(2-ethylsulfanyl-propyl)-3-hydroxy-4-methoxy-cyclohex-2-enone | IC50 is 0.038 mM for the herbicide-sensitive biotype and 0.407 mM for the herbicide-resistant biotype | Eleusine indica | |
2-[1-[(E)-allyloxyimino]-propyl]-5-(2-ethylsulfanyl-propyl)-3-hydroxy-4-methoxy-cyclohex-2-enone | IC50 is 0.054 mM for the herbicide-sensitive biotype and above 0.10 mM for the herbicide-resistant biotype | Setaria viridis | |
2-[1-[(E)-allyloxyimino]-propyl]-5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | IC50 is 0.0057 mM for the herbicide-sensitive biotype and 0.0058 mM for the herbicide-resistant biotype | Eleusine indica | |
2-[1-[(E)-allyloxyimino]-propyl]-5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | IC50 is 0.0025 mM for the herbicide-sensitive biotype and 0.038 mM for the herbicide-resistant biotype | Setaria viridis | |
3-hydroxy-5,5-dimethyl-2-[2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl]-cyclohex-2-enone | IC50 is 0.017 mM for the herbicide-sensitive biotype and 0.016 mM for the herbicide-resistant biotype | Eleusine indica | |
3-hydroxy-5,5-dimethyl-2-[2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl]-cyclohex-2-enone | IC50 is 0.0035 mM for the herbicide-sensitive biotype and 0.024 mM for the herbicide-resistant biotype | Setaria viridis | |
5-hydroxy-2,6,6-trimethyl-4-2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl-6H-[1,2]oxazin-3-one | IC50 is 0.0046 mM for the herbicide-sensitive biotype and 0.0078 mM for the herbicide-resistant biotype | Eleusine indica | |
5-hydroxy-2,6,6-trimethyl-4-2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl-6H-[1,2]oxazin-3-one | IC50 is 0.0009 mM for the herbicide-sensitive biotype and 0.008 mM for the herbicide-resistant biotype | Setaria viridis | |
5-hydroxy-2,6,6-trimethyl-4-[2-[4-(5-trifluoromethyl-pyridin-2-yloxy)-phenoxy]-propionyl]-6H-[1,2]oxazin-3-one | IC50 is 0.028 mM for the herbicide-sensitive biotype and 0.031 mM for the herbicide-resistant biotype | Eleusine indica | |
5-hydroxy-2,6,6-trimethyl-4-[2-[4-(5-trifluoromethyl-pyridin-2-yloxy)-phenoxy]-propionyl]-6H-[1,2]oxazin-3-one | IC50 is 0.0018 mM for the herbicide-sensitive biotype and 0.032 mM for the herbicide-resistant biotype | Setaria viridis | |
5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-2-[1-[(E)-ethoxyimino]-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | IC50 is 0.0043 mM for the herbicide-sensitive biotype and 0.029 mM for the herbicide-resistant biotype | Eleusine indica | |
5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-2-[1-[(E)-ethoxyimino]-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | IC50 is 0.0035 mM for the herbicide-sensitive biotype and 0.059 mM for the herbicide-resistant biotype | Setaria viridis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Setaria viridis | |
Mg2+ | - |
Eleusine indica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetyl-CoA + HCO3- | Setaria viridis | - |
ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | Eleusine indica | - |
ADP + malonyl-CoA + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Eleusine indica | - |
herbicide-sensitive and herbicide-resistant biotypes | - |
Setaria viridis | - |
herbicide-sensitive and herbicide-resistant biotypes | - |
Purification (Comment) | Organism |
---|---|
partially from young leaves by ammonium sulfate fractionation | Setaria viridis |
partially from young leaves by ammonium sulfate fractionation | Eleusine indica |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | young | Setaria viridis | - |
leaf | young | Eleusine indica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetyl-CoA + HCO3- | - |
Setaria viridis | ADP + malonyl-CoA + phosphate | - |
? | |
ATP + acetyl-CoA + HCO3- | - |
Eleusine indica | ADP + malonyl-CoA + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACCase | - |
Setaria viridis |
ACCase | - |
Eleusine indica |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
32 | - |
assay at | Setaria viridis |
32 | - |
assay at | Eleusine indica |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
assay at | Setaria viridis |
8.3 | - |
assay at | Eleusine indica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Setaria viridis | |
ATP | - |
Eleusine indica |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0009 | - |
IC50 is 0.0009 mM for the herbicide-sensitive biotype and 0.008 mM for the herbicide-resistant biotype | Setaria viridis | 5-hydroxy-2,6,6-trimethyl-4-2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl-6H-[1,2]oxazin-3-one | |
0.0018 | - |
IC50 is 0.0018 mM for the herbicide-sensitive biotype and 0.032 mM for the herbicide-resistant biotype | Setaria viridis | 5-hydroxy-2,6,6-trimethyl-4-[2-[4-(5-trifluoromethyl-pyridin-2-yloxy)-phenoxy]-propionyl]-6H-[1,2]oxazin-3-one | |
0.0025 | - |
IC50 is 0.0025 mM for the herbicide-sensitive biotype and 0.038 mM for the herbicide-resistant biotype | Setaria viridis | 2-[1-[(E)-allyloxyimino]-propyl]-5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | |
0.0035 | - |
IC50 is 0.0035 mM for the herbicide-sensitive biotype and 0.024 mM for the herbicide-resistant biotype | Setaria viridis | 3-hydroxy-5,5-dimethyl-2-[2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl]-cyclohex-2-enone | |
0.0035 | - |
IC50 is 0.0035 mM for the herbicide-sensitive biotype and 0.059 mM for the herbicide-resistant biotype | Setaria viridis | 5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-2-[1-[(E)-ethoxyimino]-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | |
0.0043 | - |
IC50 is 0.0043 mM for the herbicide-sensitive biotype and 0.029 mM for the herbicide-resistant biotype | Eleusine indica | 5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-2-[1-[(E)-ethoxyimino]-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | |
0.0046 | - |
IC50 is 0.0046 mM for the herbicide-sensitive biotype and 0.0078 mM for the herbicide-resistant biotype | Eleusine indica | 5-hydroxy-2,6,6-trimethyl-4-2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl-6H-[1,2]oxazin-3-one | |
0.0057 | - |
IC50 is 0.0057 mM for the herbicide-sensitive biotype and 0.0058 mM for the herbicide-resistant biotype | Eleusine indica | 2-[1-[(E)-allyloxyimino]-propyl]-5-[2-(5-chloro-pyridin-2-ylsulfanyl)-propyl]-4-fluoro-3-hydroxy-cyclohex-2-enone | |
0.017 | - |
IC50 is 0.017 mM for the herbicide-sensitive biotype and 0.016 mM for the herbicide-resistant biotype | Eleusine indica | 3-hydroxy-5,5-dimethyl-2-[2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propionyl]-cyclohex-2-enone | |
0.028 | - |
IC50 is 0.028 mM for the herbicide-sensitive biotype and 0.031 mM for the herbicide-resistant biotype | Eleusine indica | 5-hydroxy-2,6,6-trimethyl-4-[2-[4-(5-trifluoromethyl-pyridin-2-yloxy)-phenoxy]-propionyl]-6H-[1,2]oxazin-3-one | |
0.038 | - |
IC50 is 0.038 mM for the herbicide-sensitive biotype and 0.407 mM for the herbicide-resistant biotype | Eleusine indica | 2-[1-[(E)-allyloxyimino]-propyl]-5-(2-ethylsulfanyl-propyl)-3-hydroxy-4-methoxy-cyclohex-2-enone | |
0.051 | - |
IC50 is 0.051 mM for the herbicide-sensitive biotype and 0.067 mM for the herbicide-resistant biotype | Setaria viridis | 2,6,6-trimethyl-4-(2,4,6-trimethyl-phenyl)-[1,2]oxazinane-3,5-dione | |
0.054 | - |
IC50 is 0.054 mM for the herbicide-sensitive biotype and above 0.10 mM for the herbicide-resistant biotype | Setaria viridis | 2-[1-[(E)-allyloxyimino]-propyl]-5-(2-ethylsulfanyl-propyl)-3-hydroxy-4-methoxy-cyclohex-2-enone | |
0.076 | - |
IC50 is 0.076 mM for the herbicide-sensitive biotype and 0.227 mM for the herbicide-resistant biotype | Eleusine indica | 2,6,6-trimethyl-4-(2,4,6-trimethyl-phenyl)-[1,2]oxazinane-3,5-dione |