Application | Comment | Organism |
---|---|---|
synthesis | the presence of 10 mM L-aspartate in the production medium directly represses pyruvate carboxylase expression. This leads to limited malate flux which in turn regulates the malate/citrate antiporters resulting in increasing cis-aconitate decarboxylase activity to simultaneously convert cis-aconitate, citrate isomer, into itaconic acid | Aspergillus terreus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-aspartate | allosteric inhibitor | Aspergillus terreus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus terreus | - |
- |
- |
Aspergillus terreus Nrrl 1960 | - |
- |
- |