Organism | UniProt | Comment | Textmining |
---|---|---|---|
Yarrowia lipolytica | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Pyc1 | - |
Yarrowia lipolytica |
General Information | Comment | Organism |
---|---|---|
metabolism | simultaneous overexpression of isocitrate dehydrogenase (IDP1) and pyruvate carboxylase (PYC) gene PYC1 increase the amount of secreted alpha-ketoglutaric acid. About 19% more alpha-ketoglutaric acid in comparison with the control strain H355 are produced in bioreactor with raw glycerol as carbon source resulting in the highest yield of accumulated alpha-ketoglutaric acid of about 186 g/L after 117 h of cultivation | Yarrowia lipolytica |