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Literature summary for 6.4.1.1 extracted from
- Purification and characterization of pyruvate carboxylase from the honeybee and some properties of related biotin-containing proteins in other insects (1992), Arch. Insect Biochem. Physiol., 19, 53-66.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HgCl2 | - |
Apis mellifera |  |
| iodoacetate | - |
Apis mellifera | |
| phenylmercuric acetate | - |
Apis mellifera | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.26 | - |
pyruvate | - |
Apis mellifera | |
| 3.3 | - |
HCO3- | - |
Apis mellifera | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 128000 | - |
4 * 128000, SDS-PAGE | Apis mellifera |
| 500000 | - |
native PAGE | Apis mellifera |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aedes aegypti | - |
- |
- |
| Apis mellifera | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Apis mellifera |
| partial | Aedes aegypti |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + pyruvate + HCO3- | - |
Apis mellifera | ADP + phosphate + oxaloacetate | - |
? | |
| ATP + pyruvate + HCO3- | - |
Aedes aegypti | ADP + phosphate + oxaloacetate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 128000, SDS-PAGE | Apis mellifera |
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