Activating Compound | Comment | Organism | Structure |
---|---|---|---|
5-phospho-alpha-D-ribose 1-diphosphate | activates wild-type enzyme | Cricetulus griseus |
Protein Variants | Comment | Organism |
---|---|---|
K954E | enzyme activity in absence of effectors is slightly lower when compared with the enzyme from wild-type. UTP inhibition is reduced | Cricetulus griseus |
S974A | under conditions of saturating Utp (2 mM), mutant enzyme shows similar degree of inhibition as wild-type enzyme. Activation by 5-phosphoribosyl-alpha-pyrophosphate is completely abolished at 0.05 mM, a concentration where near maximal activation is observed with wild-type enzyme | Cricetulus griseus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
UTP | - |
Cricetulus griseus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cricetulus griseus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
CHO-K1 cell | G9C line | Cricetulus griseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + L-Gln + HCO3- | - |
Cricetulus griseus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CAD carbamoyl-phosphate synthetase | - |
Cricetulus griseus |