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Literature summary for 6.3.5.5 extracted from

  • Saeed-Kothe, A.; Powers-Lee, S.G.
    Gain of glutaminase function in mutants of the ammonia-specific frog carbamoyl phosphate synthetase (2003), J. Biol. Chem., 278, 26722-26726.
    View publication on PubMed
Search for more literature for 6.3.5.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.05
-
 ATP glutamine-dependent ADP formation Escherichia coli
0.06
-
 ATP ammonia-dependent ADP formation Escherichia coli
0.17
-
 L-glutamine
-
 Escherichia coli
111
-
 ammonia
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ATP + L-Gln + HCO3- Escherichia coli the product carbamoyl phosphate is utilized for the arginine biosynthesis 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ATP + L-Gln + HCO3-
-
 Escherichia coli 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
 ?
2 ATP + L-Gln + HCO3- the product carbamoyl phosphate is utilized for the arginine biosynthesis Escherichia coli 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
 ?
2 ATP + NH4+ + HCO3-
-
 Escherichia coli 2 ADP + phosphate + carbamoyl phosphate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.2
-
 ATP ammonia-dependent ADP formation Escherichia coli
5.1
-
 ammonia
-
 Escherichia coli
6.8
-
 ATP glutamine-dependent ADP formation Escherichia coli
9.4
-
 L-glutamine
-
 Escherichia coli