Literature summary for 6.3.5.5 extracted from

Braxton, B.L.; Mullins, L.S.; Raushel, F.M.; Reinhart, G.D.
Allosteric dominance in carbamoyl phosphate synthetase (1999), Biochemistry, 38, 1394-1401.

Search for more literature for 6.3.5.5

Activating Compound

Activating Compound	Comment	Organism	Structure
L-ornithine	effector on ATP synthesis reaction, when ornithine is bound to the enzyme, its activation dominates the actions of UMP and IMP	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
IMP	slight inhibition at 25°C	Escherichia coli
UMP	strong effect on ATP synthesis reaction	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 ATP + L-Gln + HCO3-	-	Escherichia coli	2 ADP + phosphate + L-Glu + carbamoyl phosphate	-	?
2 ATP + NH4+ + HCO3-	-	Escherichia coli	2 ADP + phosphate + carbamoyl phosphate	-	?

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Release 2023.1 (January 2023)