Literature summary for 6.3.5.3 extracted from

Morar, M.; Hoskins, A.A.; Stubbe, J.; Ealick, S.E.
Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation (2008), Biochemistry, 47, 7816-7830.

Search for more literature for 6.3.5.3

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Thermotoga maritima

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with gene products PurQ and PurS, to 3.5 A resolution. The complex has a stoichiometry of 2:1:1 for components PurS:PurQ:PurL, respectively. The flexibility of the PurS dimer is involved in the activation of the complex and the formation of an ammonia channel	Thermotoga maritima

Organism

Organism	UniProt	Comment	Textmining
Thermotoga maritima	Q9X0X3	isoform PurL	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.037	-	37°C	Thermotoga maritima

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-phosphoribosylformylglycinamide + ATP + L-glutamine + H2O	-	Thermotoga maritima	phosphoribosylformylglycinamidine + L-glutamate + ADP + phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)