Cloned (Comment) | Organism |
---|---|
- |
Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-fluoroinosine 5'-monophosphate | 50% inhibition above 2 mM | Escherichia coli | |
6-Thio-GMP | - |
Escherichia coli | |
8-aza-GMP | - |
Escherichia coli | |
GMP | 0.33 mM, 50% inhibition | Escherichia coli | |
N2-hydroxyguanosine 5'-monophosphate | 0.0003-0.0005 mM, 50% inhibition | Escherichia coli | |
oxanosine | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required for activity | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + xanthosine 5'-phosphate + L-glutamine + H2O | Escherichia coli | - |
AMP + diphosphate + GMP + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant GMPS | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + xanthosine 5'-phosphate + L-glutamine + H2O | - |
Escherichia coli | AMP + diphosphate + GMP + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GMPS | - |
Escherichia coli |
guanosine monophosphate synthetase | - |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000092 | - |
N2-hydroxyguanosine 5'-monophosphate | competitive vs XMP | Escherichia coli | |
0.33 | - |
GMP | - |
Escherichia coli | |
0.4 | - |
8-aza-GMP | - |
Escherichia coli | |
0.74 | - |
oxanosine | - |
Escherichia coli | |
3 | - |
6-Thio-GMP | - |
Escherichia coli |