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Literature summary for 6.3.4.4 extracted from

  • Vemparala, S.; Mehrotra, S.; Balaram, H.
    Role of loop dynamics in thermal stability of mesophilic and thermophilic adenylosuccinate synthetase: a molecular dynamics and normal mode analysis study (2011), Biochim. Biophys. Acta, 1814, 630-637.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + IMP + L-Asp Escherichia coli
-
GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-Asp Pyrococcus horikoshii
-
GDP + phosphate + adenylosuccinate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A7D4
-
-
Pyrococcus horikoshii O58187
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + IMP + L-Asp
-
Escherichia coli GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-Asp
-
Pyrococcus horikoshii GDP + phosphate + adenylosuccinate
-
?

Synonyms

Synonyms Comment Organism
Adenylosuccinate synthetase
-
Escherichia coli
Adenylosuccinate synthetase
-
Pyrococcus horikoshii
AdSS
-
Escherichia coli
AdSS
-
Pyrococcus horikoshii

Cofactor

Cofactor Comment Organism Structure
GTP
-
Escherichia coli
GTP
-
Pyrococcus horikoshii