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Literature summary for 6.3.4.4 extracted from

  • Hou, Z.; Wang, W.; Fromm, H.J.; Honzatko, R.B.
    IMP alone organizes the active site of adenylosuccinate synthetase from Escherichia coli (2002), J. Biol. Chem., 277, 5970-5976.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
crystals grown by the method of hanging drops Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
Hadacidin
-
Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + IMP + L-aspartate Escherichia coli catalyzing the first committed step in de novo biosynthesis of AMP GDP + phosphate + adenylosuccinate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A7D4
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + IMP + L-aspartate
-
Escherichia coli GDP + phosphate + adenylosuccinate
-
?
GTP + IMP + L-aspartate catalyzing the first committed step in de novo biosynthesis of AMP Escherichia coli GDP + phosphate + adenylosuccinate
-
?

Subunits

Subunits Comment Organism
dimer
-
Escherichia coli