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Literature summary for extracted from

  • Amici, A.; Grolla, A.A.; Del Grosso, E.; Bellini, R.; Bianchi, M.; Travelli, C.; Garavaglia, S.; Sorci, L.; Raffaelli, N.; Ruggieri, S.; Genazzani, A.A.; Orsomando, G.
    Synthesis and degradation of adenosine 5-tetraphosphate by nicotinamide and nicotinate phosphoribosyltransferases (2017), Cell Chem. Biol., 24, 553-564 .
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
H213A mutant is unable to generate adenosine 5'-tetraphosphate Homo sapiens


Organism UniProt Comment Textmining
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is able to generate adenosine 5'-tetraphosphate using substrate ATP and product phosphate, reaction of EC Accompanying a typically irreversible hydrolysis of ATP to ADP and phosphate, is a fully reversible phosphate transfer reaction between ATP and adenosine 5'-tetraphosphate Homo sapiens ?