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Literature summary for 6.3.4.21 extracted from

  • Amici, A.; Grolla, A.A.; Del Grosso, E.; Bellini, R.; Bianchi, M.; Travelli, C.; Garavaglia, S.; Sorci, L.; Raffaelli, N.; Ruggieri, S.; Genazzani, A.A.; Orsomando, G.
    Synthesis and degradation of adenosine 5-tetraphosphate by nicotinamide and nicotinate phosphoribosyltransferases (2017), Cell Chem. Biol., 24, 553-564 .
    View publication on PubMed
Search for more literature for 6.3.4.21

Protein Variants

Protein Variants Comment Organism
H213A mutant is unable to generate adenosine 5'-tetraphosphate Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme is able to generate adenosine 5'-tetraphosphate using substrate ATP and product phosphate, reaction of EC 3.6.1.14. Accompanying a typically irreversible hydrolysis of ATP to ADP and phosphate, is a fully reversible phosphate transfer reaction between ATP and adenosine 5'-tetraphosphate Homo sapiens ?
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