Literature summary for 6.3.4.2 extracted from

Aughey, G.; Grice, S.; Liu, J.
The Interplay between Myc and CTP synthase in Drosophila (2016), PLoS Genet., 12, e1005867 .

Search for more literature for 6.3.4.2

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	X2JCY2	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovarian follicle	Myc protein levels correlate with cytoophidium abundance in follicle epithelia	Drosophila melanogaster	-

General Information

General Information	Comment	Organism
physiological function	Myc protein levels correlate with cytoophidium abundance in follicle epithelia. Reducing Myc levels results in cytoophidium loss and small nuclear size in follicle cells, while overexpression of Myc increases the length of cytoophidia and the nuclear size of follicle cells. Ectopic expression of Myc induces cytoophidium formation in late stage follicle cells. Furthermore, knock-down of CTPsyn is sufficient to suppress the overgrowth phenotype induced by Myc overexpression	Drosophila melanogaster

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Release 2023.1 (January 2023)