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Literature summary for 6.3.4.2 extracted from
- Chlamydia trachomatis CTP synthetase: molecular characterization and developmental regulation of expression (1996), Mol. Microbiol., 22, 631-642.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CTP | feedback inhibitor; IC50: 0.05 mM | Chlamydia trachomatis |  |
| CTP | IC50: 0.15 mM | Escherichia coli | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.097 | - |
ATP | pH 7.2 | Chlamydia trachomatis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlamydia trachomatis | - |
- |
- |
| Escherichia coli | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| elementary body | - |
Chlamydia trachomatis | - |
| additional information | transcribed and translated primarily during the mid and late stages of the Chlamydial growth cycle | Chlamydia trachomatis | - |
| reticulate body | - |
Chlamydia trachomatis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + UTP + NH4+ | - |
Chlamydia trachomatis | ADP + phosphate + CTP | - |
? | |
| ATP + UTP + NH4+ | - |
Escherichia coli | ADP + phosphate + CTP | - |
? | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
IC50: 0.05 mM | Chlamydia trachomatis | CTP | |
| 0.15 | - |
IC50: 0.15 mM | Escherichia coli | CTP | |
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