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Literature summary for 6.3.4.2 extracted from

  • van Kuilenburg, A.B.; Meinsma, R.; Vreken, P.; Waterham, H.R.; van Gennip, A.H.
    Identification of a cDNA encoding an isoform of human CTP synthetase (2000), Biochim. Biophys. Acta, 1492, 548-552.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56180
-
x * 56180, calculation from nucleotide sequence Escherichia coli
64622
-
x * 64622, calculation from nucleotide sequence Saccharomyces cerevisiae
64783
-
x * 64783, calculation from nucleotide sequence Saccharomyces cerevisiae
65514
-
x * 65514, calculation from nucleotide sequence Mus musculus
65678
-
x * 65678, calculation from nucleotide sequence Homo sapiens
66710
-
x * 66710, calculation from nucleotide sequence Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP ?
-
?
additional information Mus musculus CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP ?
-
?
additional information Saccharomyces cerevisiae CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP ?
-
?
additional information Escherichia coli CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP ?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A7E5
-
-
Homo sapiens P17812 CTP synthetase type I
-
Homo sapiens Q9NRF8 CTP synthetase type II
-
Mus musculus P70303 CTP synthetase type I
-
Mus musculus P70698 CTP synthetase type II
-
Saccharomyces cerevisiae P28274 URA7
-
Saccharomyces cerevisiae P38627 URA8
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + UTP + NH4+
-
Homo sapiens ADP + phosphate + CTP
-
?
ATP + UTP + NH4+
-
Mus musculus ADP + phosphate + CTP
-
?
ATP + UTP + NH4+
-
Saccharomyces cerevisiae ADP + phosphate + CTP
-
?
ATP + UTP + NH4+
-
Escherichia coli ADP + phosphate + CTP
-
?
additional information CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP Homo sapiens ?
-
?
additional information CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP Mus musculus ?
-
?
additional information CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP Saccharomyces cerevisiae ?
-
?
additional information CTP synthetase plays a pivotal role in the synthesis of CTP and dCTP Escherichia coli ?
-
?

Subunits

Subunits Comment Organism
? x * 56180, calculation from nucleotide sequence Escherichia coli
? x * 66710, calculation from nucleotide sequence Mus musculus
? x * 64783, calculation from nucleotide sequence Saccharomyces cerevisiae
? x * 64622, calculation from nucleotide sequence Saccharomyces cerevisiae
? x * 66705,calculation from nucleotide sequence Homo sapiens
? x * 65514, calculation from nucleotide sequence Mus musculus
? x * 65678, calculation from nucleotide sequence Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Escherichia coli
-
-
5.4
Saccharomyces cerevisiae
-
5.9 5.6
Saccharomyces cerevisiae
-
-
5.7
Homo sapiens
-
-
5.9
Mus musculus
-
-
6.1
Homo sapiens
-
-
6.5