Activating Compound | Comment | Organism | Structure |
---|---|---|---|
acetylglutamate | activates | Homo sapiens | |
acetylglutamate | Km: 0.15 mM | Homo sapiens | |
N-carbamoylglutamate | effective activator, Km: 2.0 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.26 | - |
ATP | - |
Homo sapiens | |
1.3 | - |
NH4+ | - |
Homo sapiens | |
2.2 | - |
ATP | HCO3- | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
160000 | - |
1 * 160000, SDS-PAGE in presence of a reducing agent | Homo sapiens |
165000 | 178000 | gel filtration, density gradient centrifugation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.5 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, stable for at least 1 month | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ATP + NH4+ + HCO3- | ATP in form of CoATP2- | Homo sapiens | 2 ADP + phosphate + carbamoyl phosphate | - |
? | |
ATP + NH4+ + CO2 + H2O | no activity with Gln | Homo sapiens | ADP + phosphate + carbamoylphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 160000, SDS-PAGE in presence of a reducing agent | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
4 h, 30% loss of activity | Homo sapiens |
46 | - |
5 min, 25% loss of activity | Homo sapiens |
55 | - |
5 min, 80% loss of activity | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens |