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Literature summary for 6.3.4.14 extracted from

  • Kondo, S.; Nakajima, Y.; Sugio, S.; Yong-Biao, J.; Sueda, S.; Kondo, H.
    Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution (2004), Acta Crystallogr. Sect. D, 60, 486-492.
    View publication on PubMed
Search for more literature for 6.3.4.14

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli JM109 Aquifex aeolicus

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor-diffusion method, X-ray analysis Aquifex aeolicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 2 * 50000 Aquifex aeolicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Aquifex aeolicus BC subunit of pyruvate carboxylase, which is involved in gluconeogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Aquifex aeolicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Aquifex aeolicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + biotin-carboxyl-carrier protein + HCO3- BC subunit of pyruvate carboxylase, BC/active site structure Aquifex aeolicus ADP + phosphate + carboxybiotin-carboxyl-carrier protein
-
 ?
additional information BC subunit of pyruvate carboxylase, which is involved in gluconeogenesis Aquifex aeolicus ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 50000 Aquifex aeolicus

Synonyms

Synonyms Comment Organism
PC-beta BC subunit of pyruvate carboxylase Aquifex aeolicus

Cofactor

Cofactor Comment Organism Structure
ATP structure of the ATP-binding site Aquifex aeolicus