Literature summary for 6.3.4.14 extracted from

Polakis, S.E.; Guchhait, R.B.; Lane, M.D.
On the possible involvement of a carbonyl phosphate intermediate in the adenosine triphosphate-dependent carboxylation of biotin (1972), J. Biol. Chem., 247, 1335-1337.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
ATP + [biotin carboxyl-carrier protein]-biotin-N6-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N6-L-lysine	carboxylation proceeds via a carboxyphosphate intermediate	Escherichia coli	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + biotin-carboxyl-carrier protein + HCO3-	-	Escherichia coli	ADP + phosphate + carboxybiotin-carboxyl-carrier protein	-	?

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Release 2023.1 (January 2023)