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Literature summary for 6.3.3.6 extracted from

  • Hamed, R.; Henry, L.; Claridge, T.; Schofield, C.
    Stereoselective production of dimethyl-substituted carbapenams via engineered carbapenem biosynthesis enzymes (2017), ACS Catal., 7, 1279-1285 .
No PubMed abstract available
Search for more literature for 6.3.3.6

Application

Application Comment Organism
synthesis stereoselctive synthesis of dimethylsubstituted carbapenams using engineered 5-carboxymethylproline synthase and carbapenam-3-carboxylate synthase Pectobacterium carotovorum

Cloned(Commentary)

Cloned (Comment) Organism
-
 Pectobacterium carotovorum

Organism

Organism UniProt Comment Textmining
Pectobacterium carotovorum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (2S,6R)-2,6-dimethyl-t-carboxymethylproline
-
 Pectobacterium carotovorum AMP + diphosphate + (3S,5S,6R)-3,6-dimethylcabapenam-3-carboxylate
-
 ?
ATP + (2S,6S)-2,6-dimethyl-t-carboxymethylproline
-
 Pectobacterium carotovorum AMP + diphosphate + (2S,3S,5S,6S)-3,6-dimethylcabapenam-3-carboxylate
-
 ?
ATP + (3R,6R)-2,6-dimethyl-t-carboxymethylproline
-
 Pectobacterium carotovorum AMP + diphosphate + (2R,3S,5S,6R)-3,6-dimethylcabapenam-3-carboxylate
-
 ?
ATP + (3R,6S)-2,6-dimethyl-t-carboxymethylproline
-
 Pectobacterium carotovorum AMP + diphosphate + (2R,3S,5S,6S)-3,6-dimethylcabapenam-3-carboxylate
-
 ?
ATP + (3S,6R)-2,6-dimethyl-t-carboxymethylproline
-
 Pectobacterium carotovorum AMP + diphosphate + (2S,3S,5S,6R)-3,6-dimethylcabapenam-3-carboxylate
-
 ?

Synonyms

Synonyms Comment Organism
CarA
-
 Pectobacterium carotovorum