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Literature summary for 6.3.3.2 extracted from

  • Bertrand, R.; Beauchemin, M.; Dayan, A.; Ouimet, M.; Jolivet, J.
    Identification and characterization of human mitochondrial methenyltetrahydrofolate synthetase activity (1995), Biochim. Biophys. Acta, 1266, 245-2549.
    View publication on PubMed
Search for more literature for 6.3.3.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0008
-
 (6S)-5-formyltetrahydropteroyl pentaglutamate mitochondrial enzyme Homo sapiens
0.0047
-
 (6R,S)-5-formyltetrahydropteroyl-Glu
-
 Homo sapiens
0.022
-
 ATP
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol 85% of the total MTHFS activity is in the cytoplasm Homo sapiens 5829
-
mitochondrion matrix Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 gel filtration, mitochondrial enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
CA-46 cell
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (6R,S)-5-formyltetrahydropteroyl-Glu
-
 Homo sapiens ?
-
 ?
ATP + (6S)-5-formyltetrahydropteroyl-pentaglutamate
-
 Homo sapiens ?
-
 ?
ATP + 5-formyltetrahydrofolate
-
 Homo sapiens ADP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?