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Literature summary for 6.3.3.2 extracted from

  • Li, M.; Collier, C.; Gritsman, H.; Bertino, J.R.
    Activity of 5,10-methenyltetrahydrofolate synthetase in rat tissues and in tumor cell lines (1990), Pteridines, 2, 75-79.
No PubMed abstract available
Search for more literature for 6.3.3.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0051
-
 5-formyltetrahydrofolate
-
 Rattus norvegicus
0.05
-
 ATP
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 5-formyltetrahydrofolate Homo sapiens
-
 ?
-
 ?
ATP + 5-formyltetrahydrofolate Rattus norvegicus key enzymatic reaction in the pathway by which 5-formyltetrahydrofolate enters the folate coenzyme pool ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
 Rattus norvegicus
-
brain low activity Rattus norvegicus
-
CEM cell T-lymphoblast cell line CEM and its methotrexate resistant subline, colon tumor cell line Homo sapiens
-
CHO cell CHO, ovary cell line and its methotrexate resistant subline Cricetulus griseus
-
colon
-
 Rattus norvegicus
-
colonic cancer cell line
-
 Cricetulus griseus
-
colonic cancer cell line T-lymphoblast cell line CEM and its methotrexate resistant subline, colon tumor cell line Homo sapiens
-
intestine
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Homo sapiens
-
liver highest activity compared to other tissues Rattus norvegicus
-
lung low activity Rattus norvegicus
-
muscle low activity Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-
testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5-formyltetrahydrofolate
-
 Cricetulus griseus ADP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?
ATP + 5-formyltetrahydrofolate
-
 Homo sapiens ADP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?
ATP + 5-formyltetrahydrofolate
-
 Rattus norvegicus ADP + phosphate + 5,10-methylenetetrahydrofolate
-
 ?
ATP + 5-formyltetrahydrofolate
-
 Homo sapiens ?
-
 ?
ATP + 5-formyltetrahydrofolate key enzymatic reaction in the pathway by which 5-formyltetrahydrofolate enters the folate coenzyme pool Rattus norvegicus ?
-
 ?