Inhibitors | Comment | Organism | Structure |
---|---|---|---|
feglymycin | isolated from Streptomyces sp. DSM 11171, 13-mer peptide, noncompetitive inhibition, the inhibition is fully reversible after dilution | Escherichia coli | |
feglymycin | isolated from Streptomyces sp. DSM 11171, 13-mer peptide, noncompetitive inhibition, the inhibition is fully reversible after dilution | Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + UDP-N-acetylmuramate + L-alanine | Staphylococcus aureus | - |
ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine | - |
? | |
ATP + UDP-N-acetylmuramate + L-alanine | Escherichia coli | - |
ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
gene murC | - |
Staphylococcus aureus | - |
gene murC | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + UDP-N-acetylmuramate + L-alanine | - |
Staphylococcus aureus | ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine | - |
? | |
ATP + UDP-N-acetylmuramate + L-alanine | - |
Escherichia coli | ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MurC | - |
Staphylococcus aureus |
MurC | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Staphylococcus aureus |
25 | - |
assay at | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Staphylococcus aureus | |
ATP | - |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0003 | - |
feglymycin | pH not specified in the publication, 25°C | Escherichia coli | |
0.001 | - |
feglymycin | pH not specified in the publication, 25°C | Staphylococcus aureus |