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Literature summary for 6.3.2.56 extracted from

  • Cheung, J.; Beasley, F.C.; Liu, S.; Lajoie, G.A.; Heinrichs, D.E.
    Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus (2009), Mol. Microbiol., 74, 594-608 .
    View publication on PubMed
Search for more literature for 6.3.2.56

Application

Application Comment Organism
synthesis the SbnCEF synthetases and decarboxylase SbnH are necessary and sufficient to produce staphyloferrin B in vitro in reactions containing component substrates L-2,3-diaminopropionic acid, citric acid and 2-oxoglutaric acid Staphylococcus aureus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
 enzyme exists as monomer and dimer, gel filtration Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate Staphylococcus aureus
-
 AMP + diphosphate + staphyloferrin B
-
 ?
ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate Staphylococcus aureus NCTC 8325
-
 AMP + diphosphate + staphyloferrin B
-
 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q2G1N1
-
-
Staphylococcus aureus NCTC 8325 Q2G1N1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate
-
 Staphylococcus aureus AMP + diphosphate + staphyloferrin B
-
 ?
ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate
-
 Staphylococcus aureus NCTC 8325 AMP + diphosphate + staphyloferrin B
-
 ?

Subunits

Subunits Comment Organism
dimer and monomer, 2 * 66400, calculated from sequence Staphylococcus aureus
monomer and dimer, 1 * 66400, calculated from sequence Staphylococcus aureus

Synonyms

Synonyms Comment Organism
sbnC
-
 Staphylococcus aureus

pI Value

Organism Comment pI Value Maximum pI Value
Staphylococcus aureus calculated from sequence
-
 4.9

General Information

General Information Comment Organism
physiological function enzyme is involved in biosynthesis of staphyloferrin B. The SbnCEF synthetases and decarboxylase SbnH are necessary and sufficient to produce staphyloferrin B in vitro Staphylococcus aureus