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Literature summary for 6.3.2.50 extracted from

  • Yun, C.S.; Motoyama, T.; Osada, H.
    Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme (2015), Nat. Commun., 6, 8758.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in the protease-deficient Saccharomyces cerevisiae strain BJ5464 Pyricularia oryzae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
173000
-
-
Pyricularia oryzae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-isoleucine + acetoacetyl-CoA Pyricularia oryzae
-
AMP + diphosphate + tenuazonic acid + CoA
-
?
ATP + L-isoleucine + acetoacetyl-CoA Pyricularia oryzae kita 1
-
AMP + diphosphate + tenuazonic acid + CoA
-
?

Organism

Organism UniProt Comment Textmining
Pyricularia oryzae
-
-
-
Pyricularia oryzae kita 1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + acetoacetyl-CoA
-
Pyricularia oryzae AMP + diphosphate + tenuazonic acid + CoA
-
?
ATP + L-isoleucine + acetoacetyl-CoA
-
Pyricularia oryzae kita 1 AMP + diphosphate + tenuazonic acid + CoA
-
?

Subunits

Subunits Comment Organism
? x * 173000, SDS-PAGE Pyricularia oryzae

Synonyms

Synonyms Comment Organism
TAS1
-
Pyricularia oryzae
TeA synthetase 1
-
Pyricularia oryzae