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Literature summary for 6.3.2.38 extracted from

  • Appanna, D.L.; Grundy, B.J.; Szczepan, E.W.; Viswanatha, T.
    Aerobactin synthesis in a cell-free system of Aerobacter aerogenes 62-1 (1984), Biochim. Biophys. Acta, 801, 437-443.
No PubMed abstract available
Search for more literature for 6.3.2.38

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide
-
 Klebsiella aerogenes
p-chloromercuribenzoate
-
 Klebsiella aerogenes

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ dependent on Klebsiella aerogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes
-
 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes 62-1
-
 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-
Klebsiella aerogenes 62-1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O no activity with beta-gamma-ATP Klebsiella aerogenes 2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O no activity with beta-gamma-ATP Klebsiella aerogenes 62-1 2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine Klebsiella aerogenes 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 62-1 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine Klebsiella aerogenes 62-1 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Klebsiella aerogenes