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Literature summary for 6.3.2.34 extracted from

  • Purwantini, E.; Loganathan, U.; Mukhopadhyay, B.
    Coenzyme F420-dependent glucose-6-phosphate dehydrogenase-coupled polyglutamylation of coenzyme F420 in Mycobacteria (2018), J. Bacteriol., 200, e00375-18 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + coenzyme F420-0 + L-glutamate Mycobacterium tuberculosis reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme GDP + phosphate + coenzyme F420-1
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?
GTP + coenzyme F420-0 + L-glutamate Mycobacterium tuberculosis ATCC 25618 reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme GDP + phosphate + coenzyme F420-1
-
?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WP79
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-
Mycobacterium tuberculosis ATCC 25618 P9WP79
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + coenzyme F420-0 + L-glutamate reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme Mycobacterium tuberculosis GDP + phosphate + coenzyme F420-1
-
?
GTP + coenzyme F420-0 + L-glutamate reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme Mycobacterium tuberculosis ATCC 25618 GDP + phosphate + coenzyme F420-1
-
?
GTP + coenzyme F420-1 + L-glutamate reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme Mycobacterium tuberculosis GDP + phosphate + coenzyme gamma-F420-2
-
?
GTP + coenzyme F420-1 + L-glutamate reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme Mycobacterium tuberculosis ATCC 25618 GDP + phosphate + coenzyme gamma-F420-2
-
?

Synonyms

Synonyms Comment Organism
FbiB
-
Mycobacterium tuberculosis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Mycobacterium tuberculosis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
assay at Mycobacterium tuberculosis