Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-cystine | 1 mM, 11% inhibition | Setaria cervi | |
NEM | IC50: 9 mM, almost complete inhibition at 20 mM | Setaria cervi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | the KM-value for gamma-L-Glu-L-Cys gives a distinctly nonlinear double-reciprocal plot | Setaria cervi | |
0.41 | - |
Gly | 37°C | Setaria cervi | |
0.95 | - |
ATP | 37°C | Setaria cervi |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Setaria cervi | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + gamma-L-Glu-L-Cys + Gly | Setaria cervi | enzyme catalyzes the final step of glutathione biosynthesis | ADP + phosphate + glutathione | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Setaria cervi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + gamma-L-Glu-L-Cys + Gly | - |
Setaria cervi | ADP + phosphate + glutathione | - |
? | |
ATP + gamma-L-Glu-L-Cys + Gly | enzyme catalyzes the final step of glutathione biosynthesis | Setaria cervi | ADP + phosphate + glutathione | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
9 | - |
IC50: 9 mM, almost complete inhibition at 20 mM | Setaria cervi | NEM |