Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.2.17 extracted from

  • McGuire, J.J.; Russell, C.A.; Balinska, M.
    Human cytosolic and mitochondrial folylpolyglutamate synthetase are electrophoretically distinct. Expression in antifolate-sensitive and -resistant human cell lines (2000), J. Biol. Chem., 275, 13012-13016.
    View publication on PubMed
Search for more literature for 6.3.2.17

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
mitochondrion
-
 Homo sapiens 5739
-
additional information distinct isoforms with different electrophoretic mobility Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens central enzyme in establishing and maintaining folylpolyglutamate pools in whole cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Purification (Commentary)

Purification (Comment) Organism
partial purification Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
CCRF-CEM cell T-lymphoblastic leukemia cell line Homo sapiens
-
K-562 cell
-
 Homo sapiens
-
leukemia cell line acute nonlymphoblastic, K562 cell Homo sapiens
-
pharynx FaDu cell line Homo sapiens
-
submaxillary gland A253 epidermoid carcinoma cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00002458
-
 K-562 cells Homo sapiens
0.00002625
-
 CCRF-CEM cells Homo sapiens
0.00003516
-
 A-253 cells Homo sapiens
0.0000545
-
 FaDu cells Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information central enzyme in establishing and maintaining folylpolyglutamate pools in whole cells Homo sapiens ?
-
 ?