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Literature summary for 6.3.1.2 extracted from
- Identification and cellular location of glutamine synthetase in human sperm (2012), Cell Tissue Res., 350, 183-187.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-glutamate + NH3 | Homo sapiens | - |
ADP + phosphate + L-glutamine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| sperm | post-acrosomal region of the perinuclear theca, a major cytoskeletal component of the sperm head | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-glutamate + NH3 | - |
Homo sapiens | ADP + phosphate + L-glutamine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Glutamine synthetase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | glutamine synthetase is the only human enzyme responsible for the de novo synthesis of glutamine, catalyzes the reaction of glutamate and ammonia. The enzyme influences sperm motility in mammals | Homo sapiens |
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