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Literature summary for 6.2.1.7 extracted from

  • Vessey, D.A.; Benfatto, A.M.
    Chemical modification of bile acid: CoA ligase (1993), Biochim. Biophys. Acta, 1203, 126-130.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
NEM biphasic effect: at short reaction times ligase activity increases, but further reaction leads to nearly complete inactivation Cavia porcellus

Inhibitors

Inhibitors Comment Organism Structure
diacetyl inactivation by modification of arginine residues, ATP protects Cavia porcellus
NEM biphasic effect: at short reaction times ligase activity increases, but further reaction leads to nearly complete inactivation Cavia porcellus
Phenylglyoxal inactivation by modification of arginine residues, ATP protects Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Cavia porcellus
-
-

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + cholate + CoA
-
Cavia porcellus AMP + diphosphate + choloyl-CoA
-
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