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Literature summary for 6.2.1.54 extracted from

  • Heaton, M.P.; Neuhaus, F.C.
    Role of D-alanyl carrier protein in the biosynthesis of D-alanyl-lipoteichoic acid (1994), J. Bacteriol., 176, 681-690.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.2.1.54

Activating Compound

Activating Compound Comment Organism Structure
DTT stimulation Lacticaseibacillus casei

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Lacticaseibacillus casei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-Alanine + ATP + ? Lacticaseibacillus casei biosynthesis of D-alanyl-lipoteichoic acid ?
-
 ?

Organism

Organism UniProt Comment Textmining
Lacticaseibacillus casei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-Ala + acyl-carrier protein acyl carrier protein of E. coli, Vibrio harveyi, Saccharopolyspora erythraea, not of Bacillus subtilis, Spinacia oleracea Lacticaseibacillus casei D-Alanyl-acyl-carrier protein + AMP + diphosphate
-
 ?
ATP + D-Ala + D-alanyl carrier protein
-
 Lacticaseibacillus casei D-Alanyl-D-alanyl carrier protein + AMP + diphosphate
-
 ?
D-Alanine + ATP + ? biosynthesis of D-alanyl-lipoteichoic acid Lacticaseibacillus casei ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
 45% loss of activity in 15 min, ATP and/or D-alanyl carrier protein enhance thermostability, acyl carrier protein facilitates inactivation Lacticaseibacillus casei

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5 8 substrates D-Ala + ATP + D-alanyl carrier protein Lacticaseibacillus casei
6.6 7 substrates D-Ala + ATP + acyl carrier protein of Escherichia coli Lacticaseibacillus casei