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Literature summary for extracted from

  • Moffet, F.J.; Wang, T.T.; Bridger, W.A
    Succinyl coenzyme A synthetase of Escherichia coli. Effects of phosphoenzyme formation and substrate binding on the reactivity and stability of the enzyme (1972), J. Biol. Chem., 247, 8139-8144.
    View publication on PubMed

General Stability

General Stability Organism
ATP or phosphate protects against trypsin inactivation Escherichia coli
phosphorylation of 1 active site histidine residue per oligomeric enzyme molecule results in a significant change in the three-dimensional structure of the enzyme to a tighter conformation, with concomittant stability Escherichia coli


Organism UniProt Comment Textmining
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + succinate + CoA
Escherichia coli ADP + phosphate + succinyl-CoA