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Literature summary for 6.2.1.5 extracted from
- Citric acid cycle enzymes of the archaebacteria: citrate synthase and succinate thiokinase (1985), FEBS Lett., 179, 120-124.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-oxoglutarate | - |
Escherichia coli |  |
| 2-oxoglutarate | no inhibition | Halobacterium salinarum | |
| 2-oxoglutarate | - |
Haloferax volcanii | |
| 2-oxoglutarate | - |
Natronobacterium gregoryi | |
| 2-oxoglutarate | no inhibition | Natronomonas pharaonis | |
| 2-oxoglutarate | - |
Priestia megaterium | |
| 2-oxoglutarate | - |
Sulfolobus acidocaldarius | |
| 2-oxoglutarate | no inhibition | Sus scrofa | |
| 2-oxoglutarate | - |
Thermoplasma acidophilum | |
| ATP | - |
Escherichia coli | |
| ATP | - |
Halobacterium salinarum | |
| ATP | - |
Haloferax volcanii | |
| ATP | - |
Natronobacterium gregoryi | |
| ATP | - |
Natronomonas pharaonis | |
| ATP | - |
Priestia megaterium | |
| ATP | - |
Sulfolobus acidocaldarius | |
| ATP | - |
Sus scrofa | |
| ATP | - |
Thermoplasma acidophilum | |
| NADH | - |
Escherichia coli | |
| NADH | - |
Halobacterium salinarum | |
| NADH | - |
Haloferax volcanii | |
| NADH | - |
Natronobacterium gregoryi | |
| NADH | - |
Natronomonas pharaonis | |
| NADH | - |
Priestia megaterium | |
| NADH | - |
Sulfolobus acidocaldarius | |
| NADH | - |
Sus scrofa | |
| NADH | - |
Thermoplasma acidophilum | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 68000 | - |
gel filtration | Thermoplasma acidophilum |
| 75000 | - |
gel filtration | Sus scrofa |
| 75000 | - |
gel filtration | Priestia megaterium |
| 136000 | - |
gel filtration | Escherichia coli |
| 170000 | - |
gel filtration | Haloferax volcanii |
| 171000 | - |
gel filtration | Natronobacterium gregoryi |
| 174000 | - |
gel filtration | Haloarcula vallismortis |
| 174000 | - |
gel filtration | Natronomonas pharaonis |
| 184000 | - |
gel filtration | Natronococcus occultus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Haloarcula vallismortis | - |
- |
- |
| Halobacterium salinarum | - |
- |
- |
| Haloferax volcanii | - |
- |
- |
| Natronobacterium gregoryi | - |
- |
- |
| Natronococcus occultus | - |
- |
- |
| Natronomonas pharaonis | - |
- |
- |
| Priestia megaterium | - |
- |
- |
| Sulfolobus acidocaldarius | - |
strain DSM639 | - |
| Sulfolobus acidocaldarius DSM 639 | - |
strain DSM639 | - |
| Sus scrofa | - |
- |
- |
| Thermoplasma acidophilum | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + succinate + CoA | no activity with GTP/GDP | Escherichia coli | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Sus scrofa | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Priestia megaterium | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Halobacterium salinarum | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Haloarcula vallismortis | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Haloferax volcanii | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Natronomonas pharaonis | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Natronobacterium gregoryi | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Natronococcus occultus | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Sulfolobus acidocaldarius | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Thermoplasma acidophilum | ADP + phosphate + succinyl-CoA | - |
? | |
| ATP + succinate + CoA | no activity with GTP/GDP | Sulfolobus acidocaldarius DSM 639 | ADP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Escherichia coli | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Sus scrofa | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Priestia megaterium | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Halobacterium salinarum | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Haloarcula vallismortis | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Haloferax volcanii | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Natronomonas pharaonis | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Natronobacterium gregoryi | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Natronococcus occultus | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Sulfolobus acidocaldarius | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Thermoplasma acidophilum | GDP + phosphate + succinyl-CoA | - |
? | |
| GTP + succinate + CoA | no activity with GDP/GTP | Sulfolobus acidocaldarius DSM 639 | GDP + phosphate + succinyl-CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Sus scrofa |
| dimer | - |
Priestia megaterium |
| tetramer | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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