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Literature summary for 6.2.1.4 extracted from
- Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit (1998), J. Biol. Chem., 273, 27573-27579.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.007 | - |
GDP | pH 8.0, 30°C | Pigeon |  |
| 0.036 | - |
CoA | pH 8.0, 30°C | Pigeon | |
| 0.036 | - |
GTP | pH 8.0, 30°C | Pigeon | |
| 0.086 | - |
succinyl-CoA | pH 8.0, 30°C | Pigeon | |
| 0.49 | - |
succinate | pH 8.0, 30°C | Pigeon | |
| 2.26 | - |
phosphate | pH 8.0, 30°C | Pigeon | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE | Pigeon |
| 44500 | - |
alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE | Pigeon |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pigeon | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pigeon |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Pigeon | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 22.1 | - |
- |
Pigeon |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + succinate + CoA | - |
Pigeon | GDP + phosphate + succinyl-CoA | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE | Pigeon |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| G-SCS | - |
Pigeon |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Pigeon | isoelectric focusing | 7.4 | 7.3 |
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Release 2023.1 (January 2023)
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