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Literature summary for 6.2.1.3 extracted from

  • Reiser, K.; Davis, M.A.; Hynes, M.J.
    Aspergillus nidulans contains six possible fatty acyl-CoA synthetases with FaaB being the major synthetase for fatty acid degradation (2010), Arch. Microbiol., 192, 373-382.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene faaB or AN8280.3, DNA and amino acid sequence determination and analysis. The faaBD strain is complemented by transformation with a plasmid containing the original gene and its flanking region as well as an Aspergillus fumigatus riboB marker gene, pKR7320, and riboflavin prototrophic transformants are selected. Expression of GFP-fusion proteins GFP-FaaA and GFPFaaB Aspergillus nidulans

Protein Variants

Protein Variants Comment Organism
additional information generation of fatA, fatB, fatC and fatD deletion strains. Deletion of faaB leads to growth defects on fatty acids but does not affect the induction of genes involved in beta-oxidation, phenotype, overview Aspergillus nidulans

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome FaaB Aspergillus nidulans 5777
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Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
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gene faaB or AN8280.3 encoding isozyme FaaB
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Synonyms

Synonyms Comment Organism
FaaA
-
Aspergillus nidulans
FaaB
-
Aspergillus nidulans
FatA
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Aspergillus nidulans
FatB
-
Aspergillus nidulans
FatC
-
Aspergillus nidulans
FatD
-
Aspergillus nidulans
fatty acyl-CoA synthetase
-
Aspergillus nidulans

Expression

Organism Comment Expression
Aspergillus nidulans FaaB but not FaaA is induced in the presence of both sort-chain fatty acids and long-chain fatty acids up

General Information

General Information Comment Organism
additional information Aspergillus nidulans contains six possible fatty acyl-CoA synthetases with FaaB being the major synthetase for fatty acid degradation. Deletion of faaB leads to growth defects on fatty acids but does not affect the induction of genes involved in boxidation Aspergillus nidulans