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Literature summary for 6.2.1.3 extracted from

  • Caviglia, J.M.; Li, L.O.; Wang, S.; DiRusso, C.C.; Coleman, R.A.; Lewin, T.M.
    Rat long chain acyl-CoA synthetase 5, but not 1, 2, 3, or 4, complements Escherichia coli fadD (2004), J. Biol. Chem., 279, 11163-11169.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
isoforms 1-5 of Rattus norvegicus long chain acyl-CoA synthetase are expressed in Escherichia coli. Specific activities are 1.6-20fold higher than wild-type control strain expressing FadD. Only ACS5 restores growth on oleate as the sole carbon source in Escherichia coli Rattus norvegicus
isoforms 1-5 of Rattus norvegicus long chain acyl-CoA synthetase are expressed in Escherichia coli. Specific activities are 1.6-20fold higher than wild-type control strain expressing FadD. Only ACS5 restores growth on oleate as the sole carbon source in Escherichia coli fad Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
long chain acyl-CoA synthetase 1
-
Rattus norvegicus
-
long chain acyl-CoA synthetase 2
-
Rattus norvegicus
-
long chain acyl-CoA synthetase 4
-
Rattus norvegicus
-
long chain acyl-CoA synthetase 5
-
Rattus norvegicus Q63151 long chain acyl-CoA synthetase 3
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + oleate + CoA
-
Rattus norvegicus AMP + diphosphate + oleoyl-CoA
-
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Synonyms

Synonyms Comment Organism
ACS1
-
Rattus norvegicus
ACS2
-
Rattus norvegicus
ACS3
-
Rattus norvegicus
ACS4
-
Rattus norvegicus
ACS5
-
Rattus norvegicus
FAdD
-
Rattus norvegicus
long chain acyl-CoA synthetase 1
-
Rattus norvegicus
long chain acyl-CoA synthetase 2
-
Rattus norvegicus
long chain acyl-CoA synthetase 3
-
Rattus norvegicus
long chain acyl-CoA synthetase 4
-
Rattus norvegicus
long chain acyl-CoA synthetase 5
-
Rattus norvegicus