Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + arachidonate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + arachidonoyl-CoA | - |
? | |
ATP + decanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + decanoyl-CoA | - |
? | |
ATP + decenoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + decenoyl-CoA | - |
? | |
ATP + docosahexaenoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + docosahexaenoyl-CoA | - |
? | |
ATP + docosenoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + docosenoyl-CoA | - |
? | |
ATP + dodecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + dodecanoyl-CoA | - |
? | |
ATP + heptadecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + heptadecanoyl-CoA | - |
? | |
ATP + hexadecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + hexadecanoyl-CoA | - |
? | |
ATP + linoleic acid + CoA | - |
Trypanosoma brucei | AMP + diphosphate + linoleoyl-CoA | - |
? | |
ATP + octadecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + octadecanoyl-CoA | - |
? | |
ATP + oleic acid + CoA | - |
Trypanosoma brucei | AMP + diphosphate + oleoyl-CoA | - |
? | |
ATP + pentadecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + pentadecanoyl-CoA | - |
? | |
ATP + tetradecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + tetradecanoyl-CoA | - |
? | |
ATP + tridecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + tridecanoyl-CoA | - |
? | |
ATP + undecanoate + CoA | - |
Trypanosoma brucei | AMP + diphosphate + undecanoyl-CoA | - |
? | |
additional information | TbACS1 prefers saturated fatty acids in the range undecanoate to tetradecanoate, TbACS3 and 4, which have 95% sequence identity, have similar specificities favouring fatty acids between tetradecanoate and heptadecanoate. In addition TbACS1, 3 and 4 function well with a variety of unsaturated fatty acids | Trypanosoma brucei | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TbACS1 | - |
Trypanosoma brucei |
TbACS3 | - |
Trypanosoma brucei |
TbACS4 | - |
Trypanosoma brucei |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | - |
tetradecanoate | enzyme TbACS1 | Trypanosoma brucei | |
1.1 | - |
tetradecanoate | enzyme TbACS3 | Trypanosoma brucei | |
1.2 | - |
tetradecanoate | enzyme TbACS4 | Trypanosoma brucei |