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Literature summary for 6.2.1.2 extracted from
- Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids (1996), Biochem. Pharmacol., 52, 1643-1646.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-Hydroxynaphthoic acid | competitive with respect to hexanoate | Bos taurus |  |
| 2-Hydroxyoctanoic acid | competitive with respect to hexanoate | Bos taurus | |
| 4-methylsalicylic acid | competitive with respect to hexanoate | Bos taurus | |
| salicylic acid | competitive with respect to hexanoate | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + hexanoate + CoA | - |
Bos taurus | AMP + diphosphate + hexanoyl-CoA | - |
? | |
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Release 2023.1 (January 2023)
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