Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-hydroxydodecanoic acid | 0.04 mM, 48% inhibition | Mus musculus | |
diflunisal | 0.002 mM, 55% inhibition | Mus musculus | |
salicylic acid | 0.05 mM, 53% inhibition | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the enzyme is responsible for glycine conjugation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.15 | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-naphthoic acid + CoA | less than 10% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + 1-naphthoyl-CoA | - |
? | |
ATP + 1-naphthylacetic acid + CoA | about 25% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + 1-naphthyl-acetyl-CoA | - |
? | |
ATP + 2-naphthylacetic acid + CoA | about 35% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + 2-naphthyl-acetyl-CoA | - |
? | |
ATP + 3-aminobenzoate + CoA | 29% of the activity with benzoate | Mus musculus | AMP + diphosphate + 3-aminobenzoyl-CoA | - |
? | |
ATP + 3-chlorobenzoate + CoA | 126% of the activity with benzoate | Mus musculus | AMP + diphosphate + 3-chlorobenzoyl-CoA | - |
? | |
ATP + 3-methoxybenzoate + CoA | 54% of the activity with benzoate | Mus musculus | AMP + diphosphate + 3-methoxybenzoyl-CoA | - |
? | |
ATP + 3-methylbenzoate + CoA | 138% of the activity with benzoate | Mus musculus | AMP + diphosphate + 3-methylbenzoyl-CoA | - |
? | |
ATP + 3-nitrobenzoate + CoA | 28% of the activity with benzoate | Mus musculus | AMP + diphosphate + 3-nitrobenzoyl-CoA | - |
? | |
ATP + 4-aminobenzoate + CoA | 19% of the activity with benzoate | Mus musculus | AMP + diphosphate + 4-aminobenzoyl-CoA | - |
? | |
ATP + 4-chlorobenzoate + CoA | 96% of the activity with benzoate | Mus musculus | AMP + diphosphate + 4-chlorobenzoyl-CoA | - |
? | |
ATP + 4-methoxybenzoate + CoA | 43% of the activity with benzoate | Mus musculus | AMP + diphosphate + 4-methoxybenzoyl-CoA | - |
? | |
ATP + 4-methylbenzoate + CoA | 114% of the activity with benzoate | Mus musculus | AMP + diphosphate + 4-methylbenzoyl-CoA | - |
? | |
ATP + 4-nitrobenzoate + CoA | 29% of the activity with benzoate | Mus musculus | AMP + diphosphate + 4-nitrobenzoyl-CoA | - |
? | |
ATP + benzoate + CoA | about 30% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + benzoyl-CoA | - |
? | |
ATP + hexanoate + CoA | - |
Mus musculus | AMP + diphosphate + hexanoyl-CoA | - |
? | |
ATP + indomethacin + CoA | less than 5% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + ? | - |
? | |
ATP + octanoate + CoA | about 50% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + octanoyl-CoA | - |
? | |
ATP + tranexamic acid + CoA | less than 10% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + tranexoyl-CoA | - |
? | |
ATP + valproic acid + CoA | less than 10% of the activity with hexanoic acid | Mus musculus | AMP + diphosphate + valproyl-CoA | - |
? | |
additional information | the enzyme is responsible for glycine conjugation | Mus musculus | ? | - |
? |