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Literature summary for 6.2.1.16 extracted from
- The role of acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, in 3T3-L1 adipocyte differentiation (2012), Biol. Pharm. Bull., 35, 1980-1985.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | enzyme downregulation by shAACS targeted lentivirus expression in 3T3-L1 cells | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Mus musculus | 5737 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| 3T3-L1 cell | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AACS | - |
Mus musculus |
| Acetoacetyl-CoA synthetase | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | knockdown of AACS inhibits differentiation of 3T3-L1 cells and suppresses expression of the adipocyte markers, peroxisome proliferator-activated receptor gamma and CCAAT/enhancer binding protein alpha | Mus musculus |
| physiological function | the enzyme has a crucial role in the mechanism of 3T3-L1 differentiation | Mus musculus |
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