Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, genotyping and phylogenetic analysis | Lonicera japonica |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Lonicera japonica |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 4-coumarate + CoA | Lonicera japonica | - |
AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
ATP + ferulate + CoA | Lonicera japonica | - |
AMP + diphosphate + feruloyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lonicera japonica | - |
var. chinensis | - |
Lonicera japonica | L7Z3F8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
flower | - |
Lonicera japonica | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 4-coumarate + CoA | - |
Lonicera japonica | AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
ATP + ferulate + CoA | - |
Lonicera japonica | AMP + diphosphate + feruloyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
4-coumarate:CoA ligase | - |
Lonicera japonica |
LJ4CL1 | - |
Lonicera japonica |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Lonicera japonica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Lonicera japonica |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme belongs to the proteins containing the GEICIRG motif, phylogeny based on AMP-dependent synthetase/ligase domain sequences, overview | Lonicera japonica |
metabolism | 4-coumarate:CoA ligases are a group of essential enzymes involved in the phenylpropanoid-derived compound pathway, which converts hydroxylated cinnamic acids into their corresponding thioesters. The PDC pathway as well as its branch pathways generates various classes of secondary compounds, including lignin, flavones, flavonols, anthocyanins, isoflavonoids, and furanocoumarins | Lonicera japonica |
additional information | putative substrate binding residues are I196, Y197, G317, G343, P349, V350, and L351 | Lonicera japonica |