Any feedback?
Literature summary for 6.2.1.11 extracted from
- Microbial metabolism and production of biotin (1988), Vitamins (Kyoto), 62, 305-315.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | - |
Mycoplana sp. |  |
| Cu2+ | - |
Mycoplana sp. | |
| EDTA | - |
Mycoplana sp. | |
| Fe3+ | - |
Mycoplana sp. | |
| Hg2+ | - |
Mycoplana sp. | |
| iodoacetic acid | - |
Mycoplana sp. | |
| Ni2+ | - |
Mycoplana sp. | |
| p-chloromercuribenzoate | - |
Mycoplana sp. | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.15 | - |
CoA | - |
Mycoplana sp. | |
| 0.3 | - |
(+/-)-dethiobiotin | - |
Mycoplana sp. | |
| 0.32 | - |
(+)-biotin | - |
Mycoplana sp. | |
| 0.43 | - |
DL-actithiazic acid | - |
Mycoplana sp. | |
| 1.3 | - |
5-(2-thienyl)-n-valerate | - |
Mycoplana sp. | |
| 2.8 | - |
ATP | - |
Mycoplana sp. | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Mycoplana sp. | |
| Mn2+ | 61% of the activation relative to Mg2+ | Mycoplana sp. | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | 57000 | - |
Mycoplana sp. |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycoplana sp. | - |
No. 166 | - |
| Mycoplana sp. No. 166 | - |
No. 166 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mycoplana sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + (+/-)-dethiobiotin + CoA | - |
Mycoplana sp. | AMP + diphosphate + dethiobiotinyl-CoA | - |
? | |
| ATP + (+/-)-dethiobiotin + CoA | - |
Mycoplana sp. No. 166 | AMP + diphosphate + dethiobiotinyl-CoA | - |
? | |
| ATP + 5-(2-thienyl)-n-valerate + CoA | - |
Mycoplana sp. | AMP + diphosphate + 5-(2-thienyl)-n-valeryl-CoA | - |
? | |
| ATP + 5-(2-thienyl)-n-valerate + CoA | - |
Mycoplana sp. No. 166 | AMP + diphosphate + 5-(2-thienyl)-n-valeryl-CoA | - |
? | |
| ATP + actithiazic acid + CoA | - |
Mycoplana sp. | AMP + diphosphate + actithiazyl-CoA | - |
? | |
| ATP + actithiazic acid + CoA | - |
Mycoplana sp. No. 166 | AMP + diphosphate + actithiazyl-CoA | - |
? | |
| ATP + biotin + CoA | highly specific for ATP | Mycoplana sp. | AMP + diphosphate + biotinyl-CoA | - |
? | |
| ATP + biotin + CoA | highly specific for ATP | Mycoplana sp. No. 166 | AMP + diphosphate + biotinyl-CoA | - |
? | |
| ATP + dethiobiotin + CoA | 52% of the activity relative to biotin | Mycoplana sp. | AMP + diphosphate + dethiobiotinyl-CoA | - |
? | |
| ATP + dethiobiotin + CoA | 52% of the activity relative to biotin | Mycoplana sp. No. 166 | AMP + diphosphate + dethiobiotinyl-CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | - |
Mycoplana sp. |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 35 | - |
- |
Mycoplana sp. |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Mycoplana sp. |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 8.5 | 25°C, 1 h, stable | Mycoplana sp. |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
