Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.2.1.1 extracted from

  • Yao, L.; Guo, X.; Gui, Y.
    Acetyl-CoA synthetase 2 promotes cell migration and invasion of renal cell carcinoma by upregulating lysosomal-associated membrane protein 1 expression (2018), Cell. Physiol. Biochem., 45, 984-992 .
    View publication on PubMed
Search for more literature for 6.2.1.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + acetate + CoA Homo sapiens
-
 AMP + diphosphate + acetyl-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NR19
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ACHN cell
-
 Homo sapiens
-
RCC 786-O cell
-
 Homo sapiens
-
renal cell carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetate + CoA
-
 Homo sapiens AMP + diphosphate + acetyl-CoA
-
 ?

Synonyms

Synonyms Comment Organism
acetyl-CoA synthetase 2
-
 Homo sapiens
ACSS2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens isoform ACSS2 expression is upregulated in renal cell carcinoma cancer tissue up

General Information

General Information Comment Organism
malfunction decreased isoform ACSS2 expression inhibits renal cell carcinoma cell migration and invasion Homo sapiens
physiological function isoform ACSS2 is an important factor for promoting renal cell carcinoma development and is essential for cell migration and invasion Homo sapiens