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Literature summary for 6.2.1.1 extracted from
- Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases (2006), Proc. Natl. Acad. Sci. USA, 103, 10230-10235.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| SIRT1 | AceCS1 is completely inactivated upon acetylation and is rapidly reactivated by SIRT3 deacetylation | Mus musculus | |
| SIRT3 | AceCS2 is completely inactivated upon acetylation and is rapidly reactivated by SIRT3 deacetylation | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | AceCS1 | Mus musculus | 5737 | - |
| mitochondrion | AceCS2 | Mus musculus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AceCS1 | - |
Mus musculus |
| AceCS2 | - |
Mus musculus |
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