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Literature summary for 6.1.1.9 extracted from
- Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa (2012), Biochem. J., 448, 297-306.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D750G | the mutation is associated with a temperature-sensitive phenotype. Although depicting slower growth at 26°C, the mutant strain is unable to grow at 37°C | Neurospora crassa |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Neurospora crassa | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-valine + tRNAVal | Neurospora crassa | - |
AMP + diphosphate + L-valyl-tRNAVal | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-valine + tRNAVal | - |
Neurospora crassa | AMP + diphosphate + L-valyl-tRNAVal | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Valyl-tRNA synthetase | - |
Neurospora crassa |
| VARS | - |
Neurospora crassa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Neurospora crassa | |
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Release 2023.1 (January 2023)
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