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Literature summary for 6.1.1.6 extracted from

  • Fukunaga, J.; Yokogawa, T.; Ohno, S.; Nishikawa, K.
    Misacylation of yeast amber suppressor tRNA(Tyr) by E. coli lysyl-tRNA synthetase and its effective repression by genetic engineering of the tRNA sequence (2006), J. Biochem., 139, 689-696.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00145
-
tRNATyrCUA
-
Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-lysine + tRNALysCUU
-
Escherichia coli AMP + L-lysyl-tRNALysCUU + diphosphate
-
?
ATP + L-lysine + tRNALysUUU
-
Escherichia coli AMP + L-lysyl-tRNALysUUU + diphosphate
-
?
ATP + L-lysine + tRNATyrCUA has a weak activity to tRNATyrCUA with L-lysine Escherichia coli AMP + L-lysyl-tRNATyrCUA + diphosphate
-
?

Synonyms

Synonyms Comment Organism
LysRS
-
Escherichia coli
Lysyl-tRNA synthetase
-
Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.013
-
tRNATyrCUA
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli