Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | short spliced variant | Trypanosoma brucei | 5829 | - |
mitochondrion | large isoform | Trypanosoma brucei | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
123500 | - |
x * 123500, short spliced variant, calculated from amino acid sequence | Trypanosoma brucei |
125900 | - |
x * 125900, mitochondrial isoform, calculated from amino acid sequence | Trypanosoma brucei |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-isoleucine + tRNAIle | Trypanosoma brucei | - |
AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? | |
ATP + L-isoleucine + tRNAIle | Trypanosoma brucei 29-13 | - |
AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Trypanosoma brucei 29-13 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-isoleucine + tRNAIle | - |
Trypanosoma brucei | AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? | |
ATP + L-isoleucine + tRNAIle | - |
Trypanosoma brucei 29-13 | AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 123500, short spliced variant, calculated from amino acid sequence | Trypanosoma brucei |
? | x * 125900, mitochondrial isoform, calculated from amino acid sequence | Trypanosoma brucei |
Synonyms | Comment | Organism |
---|---|---|
IleRS | - |
Trypanosoma brucei |
Isoleucyl-tRNA synthetase | - |
Trypanosoma brucei |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Trypanosoma brucei |
General Information | Comment | Organism |
---|---|---|
physiological function | the single trypanosomal IleRS gene is essential for normal growth and for charging of cytosolic and mitochondrial tRNAIle | Trypanosoma brucei |