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Literature summary for 6.1.1.5 extracted from

  • Airas, R.K.
    Analysis of the isoleucyl-tRNA synthetase reaction by total rate equation. Magnesium and spermidine in the tRNA kinetics (1992), Eur. J. Biochem., 210, 451-454.
    View publication on PubMed
Search for more literature for 6.1.1.5

Activating Compound

Activating Compound Comment Organism Structure
spermidine at least 2 bound Mg2+ or spermidines required for binding of tRNA to the enzyme Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
diphosphate partly inhibits the binding of tRNA Escherichia coli
tRNA partly inhibits the binding of diphosphate Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ at least 2 bound Mg2+ or spermidines required for the binding of tRNA to the enzyme Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 B
-
Escherichia coli B / ATCC 11303
-
 B
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
-
 Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
ATP + L-isoleucine + tRNAIle
-
 Escherichia coli B / ATCC 11303 AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
additional information Ile + ATP + enzyme/Ile-AMP-enzyme + diphosphate, isoleucine-dependent ATP-diphosphate exchange Escherichia coli ?
-
 ?
additional information Ile + ATP + enzyme/Ile-AMP-enzyme + diphosphate, isoleucine-dependent ATP-diphosphate exchange Escherichia coli B / ATCC 11303 ?
-
 ?