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Literature summary for 6.1.1.5 extracted from

  • Jakubowski, H.
    Proofreading in trans by an aminoacyl-tRNA synthetase. A model for single site editing by isoleucyl-tRNA synthetase (1996), Nucleic Acids Res., 24, 2505-2510.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.1.1.5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-isoleucine + tRNAIle Escherichia coli physiological function is Thr formation of Ile-tRNA and editing of inadvertently misactivated homocysteine AMP + diphosphate + L-isoleucyl-tRNAIle
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 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-isoleucine + tRNAIle
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 Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
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 ?
ATP + L-isoleucine + tRNAIle physiological function is Thr formation of Ile-tRNA and editing of inadvertently misactivated homocysteine Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
Ile-tRNAIle + 3-mercaptopropionate
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 Escherichia coli S-Isoleucyl-3-mercaptopropionate + tRNAIle
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 ?
Ile-tRNAIle + cysteamine
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 Escherichia coli tRNAIle + isoleucylcysteamine
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 ?
Ile-tRNAIle + cysteine D- and L-isomer of Lys Escherichia coli tRNAIle + isoleucylcysteine D-isoleucylcysteine and L-isoleucylcysteine ?
Ile-tRNAIle + DTT
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 Escherichia coli Thioester of Ile and DTT + tRNAIle
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 ?
Ile-tRNAIle + L-cysteine methyl ester
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 Escherichia coli tRNAIle + isoleucyl-L-cysteine methyl ester
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 ?
Ile-tRNAIle + N-acetylcysteine
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 Escherichia coli S-isoleucyl-N-acetylcysteine + tRNAIle
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 ?