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Literature summary for 6.1.1.4 extracted from

  • Montanari, A.; De Luca, C.; Frontali, L.; Francisci, S.
    Aminoacyl-tRNA synthetases are multivalent suppressors of defects due to human equivalent mutations in yeast mt tRNA genes (2010), Biochim. Biophys. Acta, 1803, 1050-1057.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene LARS1 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
gene LARS1
-

Synonyms

Synonyms Comment Organism
Leucyl-tRNA synthetase
-
Homo sapiens

General Information

General Information Comment Organism
additional information human leucyl-tRNA synthetase and mitochondrial protein elongation factor EF-Tu show suppressing cross-activity on different tRNA mutants in humans and Saccharomyces cerevisiae, mechanism and specificity of suppression, overview. Suppressive activities of wild-type and mutant enzymes, overview Homo sapiens